Recommended antıvırus exclusıons for System Center Vırtual Machine Manager and managed hosts

Standard
  • All VHD, VHDX, AVHD, AVHDX, VSV, and ISO files that are stored in the SCVMM libraries and library shares
  • All VHD, VHDX, AVHD, AVHDX, VSV, and ISO files that are stored on the Hyper-V hosts and host clusters. These file types are typically found in the following locations:
    • Default virtual machine configuration directory and its subdirectories, if they are used
      • C:\ProgramData\Microsoft\Windows\Hyper-V
    • Default virtual machine virtual hard disk files directory and its subdirectories, if they are used
      • C:\Users\Public\Documents\Hyper-V\Virtual Hard Disks
    • Default snapshot files directory and its subdirectories, if they are used
      • C:\ProgramData\Microsoft\Windows\Hyper-V\Snapshots
    • Default Cluster Shared Volumes (CSV) paths and any subdirectories if you use Cluster Shared Volumes.
      • C:\ClusterStorage
    • Any applicable custom virtual hard disk drive directories
    • Any custom replication data directories if you use Hyper-V Replica or protect virtual machine workloads in Azure (for example, Azure Site Recovery [ASR] Services)Notes
  • If you’re storing virtual machine files on SMB 3.0 file shares and have antivirus software that’s running on your file servers, set the appropriate exclusions (as noted earlier) on the file server.
  • The following two Hyper-V processes may have to be set as process exclusions in the antivirus software on all Hyper-V hosts:
    • Vmms.exe
    • Vmwp.exe
  • If virtual machines are missing from the Hyper-V Management console, you must set the antivirus exclusions and then restart the Hyper-V Virtual Machine Management service.
  • If you receive error code 0x800704C8, the virtual machine configuration file was likely corrupted. If you receive this error and can’t fix the issue by restarting the Hyper-V Virtual Machine Management service, the virtual machine must be re-created or restored from a backup.

https://support.microsoft.com/en-us/kb/3119208